Autonomic

Drugs that turn the parasympathetic "rest-and-digest" system up (cholinergics) or down (anticholinergics) — mirror-image classes anchored by atropine, the bradycardia and organophosphate antidote.

2 drug classes 8 key drugs

Cholinergic Agonists

High-yield

Turn UP "rest-and-digest." Used for urinary retention & myasthenia. Overdose = cholinergic crisis (SLUDGE).

Anticholinergics (Atropine)

High-yield

Block "rest-and-digest." Atropine treats bradycardia; classic toxidrome — "can’t see/pee/spit/poop."