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Mental & Behavioral Health

Personality Disorders

Borderline personality disorder (BPD) Verified · Sep 2026

StatPearls: "Personality disorders are currently described as pervasive, maladaptive, and chronic patterns of behavior, thinking, and feeling." In our own words: a long-lasting, rigid way of thinking, feeling and acting that is far out of step with the person's culture, starts by adolescence or early adulthood, and causes distress or impairment.

People with personality disorders often do not see their own patterns as the problem, and staff often feel pulled between rescuing and rejecting them. The nurse keeps everyone safe, screens for suicide at every contact, sets clear limits that the whole team enforces the same way, stays calm and neutral, and supports psychotherapy — the treatment that actually helps.

What’s going wrong in the body

The normal physiology, where it fails, and why the body’s compensation backfires.

01 What makes a personality pattern a disorder

"Patients with personality disorders often have distorted perceptions of reality and abnormal affective behavior, manifesting in maladaptive coping mechanisms and distress" (StatPearls). The pattern is pervasive, rigid and long-lasting rather than a reaction to one situation.

Insight is often poor. "Generally, individuals with personality disorders have a poor understanding of how their behaviors are related to their feelings, dysregulated emotions, and interpersonal difficulties." "Often, individuals request treatment at the behest of a first-degree relative or friend. Generally, this occurs after maladaptive behaviors have created stress on another rather than internal distress from the individual with a personality disorder" (StatPearls).

Onset. "The features of personality disorders typically start emerging in adolescence, and worsening pathological behaviors may increase through early adulthood before they become an inflexible pattern of thinking and action" (StatPearls). Open RN: "Formal diagnosis of a personality disorder is not made before age 18, but traits may be present earlier."

Three clusters. "The 10 personality disorders are classified into 3 clusters. Cluster A includes paranoid, schizoid, and schizotypal personality disorders. Cluster B includes antisocial, borderline, histrionic, and narcissistic personality disorders. Cluster C includes avoidant, dependent, and obsessive-compulsive personality disorders" (StatPearls). "Despite the historical division of personality disorders into clusters, this approach has limitations and lacks consistent validation in the literature."

Cluster membership as StatPearls lists it; this page focuses on borderline and antisocial personality disorder (StatPearls).

02 [BPD] Borderline personality disorder — emotion, abandonment and splitting

NIMH: "Borderline personality disorder is a serious mental illness that affects how a person feels about themselves and others and makes it hard to function in everyday life. The disorder often involves difficulty regulating emotions, leading to impulsivity, an unstable or often changing sense of self, and troubled relationships with others."

All-or-nothing thinking. People with BPD "tend to view things in extremes, such as all good or all bad. This is often seen in social interactions, which may swing from extreme closeness to extreme dislike, resulting in unstable relationships and emotional pain" (NIMH). StatPearls: "Splitting is a defense mechanism in which a person cannot form a realistic view of another person."

Abandonment fear. "Fear of abandonment can drive maladaptive behaviors, including impulsivity, self-harm, and suicidal behavior" (StatPearls). "Individuals with BPD may display marked emotional lability, including the potential to react strongly and become angry, violent, or suicidal."

The brain. "Top-down control abnormalities are seen in borderline personality disorder, showing that cortical activity to moderate the amygdala (and other limbic areas) is impaired. Instead, behavior is driven from the bottom-up, meaning that amygdala activation is unmoderated by higher-level cortical functions" (StatPearls).

Causes. "research suggests that genetic, physical, environmental, and social factors may increase the risk of developing the disorder"; "Many people with borderline personality disorder report experiencing traumatic life events, such as abuse, neglect, maltreatment, abandonment, or hardship during childhood" (NIMH).

Emotion that runs ahead of control, fear of abandonment, splitting and impulsive coping feed each other in BPD (NIMH, StatPearls).

03 [ASPD] Antisocial personality disorder

"Antisocial personality disorder (ASPD) encompasses a chronic pattern of disregard for the rights of others, impaired empathy, deceitfulness, impulsivity, and persistent behavioral dysfunction that often begins with conduct disorder in childhood or adolescence." "Individuals with ASPD often manipulate others for personal gain, lack empathy, and seldom feel remorse for their actions" (StatPearls). In our own words: the diagnosis is made in adults, with conduct problems beginning in childhood.

Conduct disorder. "While most children with conduct disorder will not develop ASPD, conduct disorder is a significant risk factor for its development," with "males being more likely than females to progress to ASPD in adulthood" (StatPearls).

Biology and environment. "Underarousal of the autonomic nervous system has been hypothesized as a pathophysiological mechanism for antisocial personality disorder" (StatPearls). "Specifically, maltreated children with the low-activity variant of the MAO-A gene were significantly more likely to develop conduct disorder and ASPD."

Psychopathy is related but narrower. "While most individuals meeting the criteria for psychopathy also meet the criteria for ASPD, the reverse is not true" (StatPearls).

Treatment goals. "Early treatment for children with conduct disorder is considered the most effective and least costly way to prevent or treat ASPD." "Since ASPD is unlikely to remit, treatment should focus on reducing interpersonal conflict and stabilizing psychosocial functioning" (StatPearls).

Conduct disorder is the main precursor of ASPD, though most children with it do not progress; treatment aims at harm reduction (StatPearls).

Causes & risk factors

Modifiable factors are teaching targets — the patient can act on them.

Temperament plus life experience — "Temperament is a heritable and innate psychobiological characteristic that significantly contributes to personality development," "further shaped through epigenetic mechanisms, namely, life experiences such as trauma and socioeconomic conditions" (StatPearls) [BPD] Family history, brain changes and childhood trauma — "abuse, neglect, maltreatment, abandonment, or hardship during childhood" (NIMH) [ASPD] Childhood conduct disorder; maltreatment with the low-activity MAO-A variant (StatPearls) Medical causes of personality change — "head trauma, cerebrovascular diseases, cerebral tumors, epilepsy, Huntington disease, multiple sclerosis, endocrine disorders, heavy metal poisoning, neurosyphilis, and acquired immune deficiency syndrome (AIDS)" (StatPearls) Prevalence (attributed) — StatPearls cites a WHO estimate of 6.1% for any personality disorder; BPD "0.7% to 2.7%" in the general population; ASPD "2% to 3%" in the general population

Signs & symptoms

Each finding tied to the mechanism that produces it — and the triage it calls for.

[BPD] Intense, unstable relationships and fear of abandonment early Expected
Why: NIMH: "Avoiding real or perceived abandonment, such as by jumping into or out of relationships quickly" and "A pattern of intense and unstable relationships with family, friends, and loved ones."
[BPD] Rapid mood swings lasting hours to days; chronic emptiness; intense anger Expected
Why: NIMH: "Intense and highly variable moods, with episodes lasting from a few hours to a few days," "Chronic feelings of emptiness," "Inappropriate, intense anger or problems controlling anger." "The pattern of mood instability differs from a depressive episode or manic episode, both of which have more consistent mood symptoms" (StatPearls).
[BPD] Splitting — staff seen as all good or all bad Hold & notify
Why: "Splitting is common, with individuals viewing others as entirely good or entirely bad from moment to moment" (StatPearls). Open RN: "Clients may view staff as all good or all bad, leading to division."
[BPD] Impulsive, risky behavior Hold & notify
Why: NIMH: "spending sprees, unsafe sex, substance use, dangerous driving, and binge eating." If these happen mostly during elevated mood, they may point to a mood disorder instead (NIMH).
[BPD] Brief paranoia or dissociation under stress Hold & notify
Why: "Transient paranoia is frequently associated with borderline personality disorder, but auditory hallucinations are not a primary symptom" (StatPearls). "Frank and persistent psychosis is not consistent with a personality disorder" — report persistent psychotic symptoms for evaluation.
Superficial self-injury (for example, a new scratch or cut) — assess for intent to die Hold & notify
Why: "Self-harming behavior can include either nonsuicidal self-harm or suicidal behavior with intent to die." "self-harming behavior is a risk factor for future suicide." "Clinicians should carefully assess any self-harming behavior for intent to die" (StatPearls).
Thoughts of suicide or self-harm, a suicide attempt, or a life-threatening situation Report immediately
Why: NIMH: "Anyone thinking of harming themselves or attempting suicide needs help right away"; "If you or someone you know is struggling or having thoughts of suicide, call or text the 988 Suicide & Crisis Lifeline"; "In life-threatening situations, call 911."
Escalating aggression toward others that de-escalation does not stop Report immediately
Why: Open RN: "If the client continues to escalate, measures must be taken to keep the client and others safe," and "If interventions are not effective in de-escalating a client at risk to themselves or others, seclusion or restraints may be required."
[ASPD] Manipulation, deceit, lack of remorse Expected
Why: "Individuals with ASPD often manipulate others for personal gain, lack empathy, and seldom feel remorse for their actions" (StatPearls).

Diagnostics

Test In this disorder Normal
Longitudinal clinical assessment "Diagnosis of a personality disorder is based on the longitudinal observation of an individual's behaviors to assess their functioning over time." "If possible, personality disorders should be diagnosed when there is not a concurrent acute psychiatric condition" (StatPearls). BPD "is usually diagnosed in late adolescence or early adulthood" (NIMH). Pattern seen over time, ideally outside an acute psychiatric episode StatPearls, NIMH —
Medical and substance evaluation "If the symptoms are first presenting in midlife, the individual should be evaluated for another medical condition or an unrecognized substance use disorder" (StatPearls). NIMH: "A medical exam can further rule out other possible causes." Rule out medical causes, especially if symptoms first appear in midlife StatPearls, NIMH —
Mental status and safety screen StatPearls: assess "thoughts of self-harm, suicidality, or harming others," and "individuals with personality disorders should be screened for suicidal ideation regularly." Open RN: introduce suicide screening "in a way that helps the client understand its purpose." Ask about self-harm, suicide and harming others at every assessment StatPearls, Open RN —
Co-occurring conditions NIMH lists these; "symptoms of borderline personality disorder occur in the absence of significantly elevated mood seen during manic or hypomanic episodes, which is a key feature of bipolar disorder." "The prevalence of ASPD in patients with alcohol use disorder ranges from 16% to 49%" (StatPearls). Depression, PTSD, bipolar disorder, anxiety, substance use and eating disorders are common with BPD NIMH, StatPearls —

Complications

Black-box warning — most severe: ■ [BPD] Suicide and self-harm Report immediately
"People with borderline personality disorder have a significantly higher rate of self-harm and suicidal thoughts and behavior than the general population" (NIMH). "Comorbid major depressive disorder is another risk factor for suicide" (StatPearls).
"Men with BPD may have greater functional impairment, impulsivity, and aggression than women with BPD and may be at higher risk of dying by suicide" (StatPearls). Thoughts of suicide → 988; "In life-threatening situations, call 911" (NIMH). "Suicidal behaviors tend to remit over time, although suicidality may continue when BPD symptoms are untreated or severe or when functional impairment persists" (StatPearls).
Warning: Aggression and violence Report immediately
Open RN: "Individuals diagnosed with personality disorder may be suicidal, self-mutilating, impulsive, angry, manipulative, or aggressive." "Any threats should be taken seriously."
De-escalation first: "Speaking in a calm voice," "Offering options instead of trying to take control," "Providing space so the client doesn’t feel trapped." Seclusion or restraint only "If interventions are not effective in de-escalating a client at risk to themselves or others" (Open RN).
Warning: Substance use Hold & notify
"Substance use disorders are common among personality disorders" (StatPearls). "Maladaptive coping is inherent in the diagnosis of BPD and may include substance use, impulsive spending, high-risk sexual behavior, binge eating, reckless driving, self-harm, or self-sabotaging behaviors."
Open RN: "Benzodiazepines can be especially toxic when combined with alcohol or opioids, and they can also cause behavioral disinhibition in clients with personality disorders."
Caution: Countertransference and team splitting
"Clinicians must recognize signs of countertransference, which can negatively affect patient care" (StatPearls). "Patients with BPD can be challenging to treat due to splitting dynamics, and clinicians should maintain clear boundaries within the clinician-patient relationship."
Open RN: "Maintain team communication and a unified, consistent approach. Avoid taking sides or reacting emotionally."
Caution: [ASPD] Hospital disruption
"Hospitalization is not cost-effective, as it provides little to no benefit for those with ASPD. Additionally, the behavior of patients with ASPD in a psychiatric hospital can disrupt the therapeutic environment for other patients" (StatPearls).
Admission "should be reserved for treating concurrent psychiatric conditions or complications, such as substance intoxication or withdrawal, or recent suicidal behavior."

Medications for this condition

Why each class is prescribed here — every card links to its full pharmacology page.

Beyond medications

  • [BPD] Psychotherapy is first-line. "The first-line treatment for BPD is psychotherapy" (StatPearls). NIMH: "Psychotherapy, or talk therapy, is the primary treatment for borderline personality disorder."
  • [BPD] Dialectical behavior therapy (DBT). "This treatment was developed specifically for people with borderline personality disorder. DBT uses concepts of mindfulness or awareness of one’s present situation and emotional state. DBT also teaches skills to help people control intense emotions, reduce self-destructive behaviors, and improve relationships" (NIMH). "Treatment with DBT combines individual therapy, group therapy, and weekly team consultations for the therapists" (StatPearls). Open RN: "It is considered the gold standard for treating borderline personality disorder and is also used for other types of disorders."
  • [BPD] Other therapies. Mentalization-based therapy "helps patients with BPD regulate emotions by increasing their mentalizing capacity and reflective functioning" (StatPearls); "CBT can help reduce mood swings, anxiety symptoms, and self-harming or suicidal behaviors" (NIMH).
  • [ASPD] Realistic goals. "Psychotherapy for ASPD has limited evidence of efficacy, in large part due to poor patient motivation, lack of insight, and difficulty forming a therapeutic alliance" (StatPearls); the aim is harm reduction and better functioning.
  • Case management and family. "Case management can assist patients with personality disorders in maintaining income, shelter, and connection to medical and mental health services" (StatPearls). "Involving the patient's family is another way of monitoring for decompensation."
  • Stay in treatment. "It is also important to not only seek out—but stick with—treatment" (NIMH).

Nursing considerations

The RN-specific layer — each action paired with the reason it matters.

Safety
Screen for suicide, self-harm and harm to others at every contact, and take every threat seriously.
Why: Open RN: "Any threats should be taken seriously." StatPearls: screen "for suicidal ideation regularly."
Develop a crisis/safety plan with the client.
Why: Open RN: it identifies "thoughts or behaviors that increase the risk of harming self or others," triggers, "Implementing coping strategies," and "Reaching out to other coping resources."
Care for self-inflicted wounds per agency policy, neutrally and matter-of-factly, and assess for intent to die.
Why: Open RN: "remaining neutral and dressing the client’s self-inflicted wounds in a matter-of-fact manner." StatPearls: "assess any self-harming behavior for intent to die."
Use de-escalation early; seclusion or restraint only if it fails and someone is at risk.
Why: Open RN: calm voice, options, space; restraint "may be required" only if de-escalation is not effective.
Limits, boundaries and the team
Set clear boundaries and limits early and enforce them the same way across the whole team.
Why: Open RN: "Clear boundaries and limits should be set and consistently reinforced by the health care team." "Consistent enforcement of limits fosters safety, trust, and structure."
Watch for splitting; share information at handoff and avoid taking sides.
Why: Open RN: "Maintain team communication and a unified, consistent approach. Avoid taking sides or reacting emotionally."
When behavior problems emerge, calmly review goals, limits and boundaries with the client.
Why: Open RN: "the nurse should calmly review therapeutic goals, limits, and boundaries with the client."
Notice your own reactions (countertransference) and seek supervision.
Why: StatPearls: countertransference "can negatively affect patient care."
Communication and teaching
Use calm, neutral, non-reactive language; be direct and honest; validate feelings without encouraging harmful behavior.
Why: Open RN tips: "Use calm, neutral, and non-reactive language." "Be direct, honest, and transparent." "Validate feelings without encouraging distorted behaviors."
Avoid power struggles and "rescuing" behaviors.
Why: Open RN: "Avoid power struggles or confrontation."
Teach families to take comments about self-harm seriously and how to reach 988.
Why: NIMH: "Take comments about possible self-harm or suicide seriously. Encourage prompt contact with a mental health professional or the 988 Suicide & Crisis Lifeline."
Encourage structure and staying in therapy.
Why: NIMH: "Encourage structure through daily scheduling and prioritizing a healthy lifestyle."

How a real nurse thinks

The clinical-judgment loop, worked for a typical presentation — reasoning, not reference.

  1. 1
    Recognize cues

    A comment suggesting thoughts of death, new self-harm, rapid mood swings, splitting (one nurse ideal, another useless), and a limit that was bent by the team.

  2. 2
    Analyze cues

    Self-harm "is a risk factor for future suicide" and must be assessed "for intent to die" (StatPearls). Splitting divides staff, and inconsistent limits feed it (Open RN).

  3. 3
    Prioritize

    Safety first: assess suicide risk and the new wound now. Then restore a consistent limit and unify the team.

  4. 4
    Generate solutions

    Suicide assessment with the provider; neutral wound care; update the safety plan; calmly restate the phone rule; share the splitting pattern and agree one approach at handoff.

  5. 5
    Take action

    Ask directly about suicidal thoughts and intent, notify the provider, increase observation per policy, dress the scratch in a matter-of-fact way, and restate the limit calmly without arguing. Report the team inconsistency.

  6. 6
    Evaluate

    Her safety plan is updated with coping steps she chose, staff give the same answer about the phone rule, and she attends the next DBT skills group.

Scenario — you’re the nurse

Work each question before revealing the answer. Rationales explain the wrong options too.

Inpatient psychiatric unit · evening shift

A 23-year-old woman with borderline personality disorder was admitted after superficial cuts to her forearm following a breakup. On the day shift she praised one nurse as ‘the only one who understands me.’

Behavior — now calls the evening nurse ‘useless’ and asks to break the unit phone rule ‘just this once’
Mood — tearful, then angry, within 20 minutes
Safety — new superficial scratch on her wrist; says ‘Nobody would care if I died’
Team — day nurse has left a note that the phone rule was bent yesterday
Q1 Select all that apply
Which nursing actions are appropriate for a client with borderline personality disorder who splits staff? Select all that apply.
  1. A. Set clear limits and have the whole team enforce them the same way
  2. B. Share information at handoff and avoid taking sides
  3. C. Let the "favorite" nurse make exceptions to keep the client calm
  4. D. Use calm, neutral, non-reactive language
  5. E. Argue until the client admits the behavior is wrong
Reveal answer & rationale
Answer: A, B, D
Open RN: "Clear boundaries and limits should be set and consistently reinforced by the health care team"; "Maintain team communication and a unified, consistent approach. Avoid taking sides or reacting emotionally"; "Use calm, neutral, and non-reactive language"; "Avoid power struggles or confrontation." Exceptions by one nurse feed splitting.
Q2 Multiple choice
A client with BPD says, ‘Nobody would care if I died.’ What is the nurse’s priority action?
  1. A. Change the subject to reduce attention-seeking
  2. B. Ask directly about suicidal thoughts and intent and keep the client safe while notifying the provider
  3. C. Document it and review at the next weekly meeting
  4. D. Tell the client that people care about her
Reveal answer & rationale
Answer: B
NIMH: "Anyone thinking of harming themselves or attempting suicide needs help right away." StatPearls: screen for suicidal ideation regularly and "assess any self-harming behavior for intent to die." Open RN: "Any threats should be taken seriously."
Q3 Multiple choice
Which statement about treatment for borderline personality disorder is accurate?
  1. A. An FDA-approved medication is the first-line treatment
  2. B. Psychotherapy is first-line; DBT was developed specifically for BPD
  3. C. Hospitalization cures the disorder
  4. D. BPD never improves
Reveal answer & rationale
Answer: B
"The first-line treatment for BPD is psychotherapy" and "No medications are approved by the US Food and Drug Administration for the treatment of BPD" (StatPearls). DBT "was developed specifically for people with borderline personality disorder" (NIMH). StatPearls reports mean remission rates of 60% at 5–15 years.
Q4 Multiple choice
A client with antisocial personality disorder asks to be admitted to ‘work on his personality.’ Which fact guides the response?
  1. A. Admission is the main treatment for ASPD
  2. B. Hospitalization gives little benefit for ASPD itself and is reserved for concurrent conditions or complications
  3. C. A mood stabilizer cures ASPD
  4. D. ASPD always remits by age 25
Reveal answer & rationale
Answer: B
StatPearls: "Hospitalization is not cost-effective, as it provides little to no benefit for those with ASPD" and "should be reserved for treating concurrent psychiatric conditions or complications, such as substance intoxication or withdrawal, or recent suicidal behavior." No medication is FDA-approved for ASPD.

Common questions

What causes personality disorders?
Common causes and risk factors include temperament plus life experience — "temperament is a heritable and innate psychobiological characteristic that significantly contributes to personality development," "further shaped through epigenetic mechanisms, namely, life experiences such as trauma and socioeconomic conditions" (statpearls), [bpd] family history, brain changes and childhood trauma — "abuse, neglect, maltreatment, abandonment, or hardship during childhood" (nimh), [aspd] childhood conduct disorder; maltreatment with the low-activity mao-a variant (statpearls), medical causes of personality change — "head trauma, cerebrovascular diseases, cerebral tumors, epilepsy, huntington disease, multiple sclerosis, endocrine disorders, heavy metal poisoning, neurosyphilis, and acquired immune deficiency syndrome (aids)" (statpearls), prevalence (attributed) — statpearls cites a who estimate of 6.1% for any personality disorder; bpd "0.7% to 2.7%" in the general population; aspd "2% to 3%" in the general population.
What are the early signs of personality disorders?
Early findings include [BPD] Intense, unstable relationships and fear of abandonment.
Do people with borderline personality disorder get better?
Often, yes. StatPearls reports "mean remission rates of 60%" at 5 to 15 years, though "psychosocial functioning often remains impaired," and "Suicidal behaviors tend to remit over time."
Is there a medication for personality disorders?
No medicine is FDA-approved for any personality disorder (StatPearls; Open RN). NIMH says medication "is not a first-line treatment" for BPD but may help co-occurring symptoms.
Why does the whole team need the same rules?
Because splitting divides staff: "Clients may view staff as all good or all bad, leading to division" (Open RN). "Consistent enforcement of limits fosters safety, trust, and structure."
Are hallucinations part of personality disorders?
Brief paranoia can occur, especially in BPD, but "Frank and persistent psychosis is not consistent with a personality disorder" (StatPearls).

Sources

Reviewed by Hae Suk Lee, RN

Educational summary for nursing students. Scenarios are fictional teaching cases. Always verify against current guidelines and your institution's protocols before acting in practice. Not medical advice.

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