Conjunctivitis (Pink Eye)
Pink eye Verified · Sep 2026NEI: "Pink eye, or conjunctivitis, causes swelling and redness in the inside of your eyelid and the white part of your eye. Your eye may also feel itchy and painful." StatPearls: "Conjunctivitis is a common, treatable, and typically benign eye condition."
Pink eye is common and usually benign, but the nurse has three jobs: stop the spread (hand hygiene, no shared towels or drops), sort the likely cause (watery with a cold, thick pus, or itchy and bilateral), and catch the red eye that is something else — pain, photophobia, blurred vision that does not clear with blinking, or a contact-lens wearer. Antibiotics do not help viral pink eye, and steroid eye drops belong under an eye specialist’s direction.
What’s going wrong in the body
The normal physiology, where it fails, and why the body’s compensation backfires.
01 The conjunctiva and its three common attackers
"The conjunctiva is the transparent, lubricating mucous membrane covering the eye’s outer surface with 2 main parts: the bulbar conjunctiva, which covers the globe, and the tarsal conjunctiva, which lines the eyelids' inner surfaces." When it is inflamed, the result is conjunctivitis, which "manifests as engorgement of blood vessels" — a red eye — with pain and discharge (StatPearls).
Causes. "Conjunctivitis is caused by viruses, bacteria, allergens, contact lens use, chemicals, fungi, and certain diseases" (CDC). "Among adults, viral conjunctivitis is the most frequent infectious cause, followed by bacterial conjunctivitis. About 80% of acute conjunctivitis cases are viral" (StatPearls), mostly adenovirus. "Bacterial conjunctivitis is more common in children than adults" (StatPearls).
How it spreads. "Viral conjunctivitis is very contagious and mostly spread through hand-to-eye contact by hands or objects that are contaminated with the virus" (CDC). "Bacterial conjunctivitis is very contagious and can spread from person to person in many ways," including sexual contact "with eye to genital contact, or vertically from mother to baby." "Allergic conjunctivitis is not contagious" (CDC).
Timing terms. "Hyperacute conjunctivitis occurs during the acute period, with a rapid onset of typically severe symptoms within 24 hours." "Chronic conjunctivitis describes symptoms lasting longer than 4 weeks" (StatPearls).
02 Allergic conjunctivitis — a mast-cell reaction
"IgE molecules bind with high affinity to type I Fc ε receptors (FcεRIs) on conjunctival mast cells, priming the ocular surface for subsequent allergic responses." "Upon reexposure, allergens cross-link adjacent IgE molecules on mast cell surfaces, resulting in rapid degranulation" (StatPearls).
"Preformed mediators, including histamine, tryptase, chymase, and heparin, are released within minutes and produce vasodilation, increased vascular permeability, conjunctival edema, hyperemia, itching, and tearing." "Histamine stimulates sensory nerve endings within the conjunctiva, producing the characteristic itching associated with allergic conjunctivitis" (StatPearls).
Why not rub. "Eye rubbing should be discouraged because mechanical stimulation can trigger mast cell degranulation and worsen symptoms" (StatPearls). This is also why antihistamines and mast-cell stabilizers are the core drugs.
03 When a red eye is dangerous
Hyperacute bacterial conjunctivitis. "A very rare and severe type of conjunctivitis with rapid onset and progression" with "massive exudate, severe chemosis, eyelid swelling, marked hyperemia, pain, and decreased vision" (CDC). "Causative organisms in hyperacute conjunctivitis include Neisseria gonorrhea" and Neisseria meningitidis, and it "can lead to rapid corneal perforation, systemic involvement, and even death" (StatPearls). "Gonococcal conjunctivitis and primary meningococcal conjunctivitis are ophthalmic emergencies with risks of vision loss and death" (StatPearls).
It may not be conjunctivitis at all. "Some signs and symptoms that point to a diagnosis other than conjunctivitis include sectoral redness, ciliary flush, elevated intraocular pressure, vision loss, moderate to severe pain, hypopyon (white or whitish-yellow collection of inflammatory cells in the anterior chamber), hyphema (collection of blood in the anterior chamber), pupil asymmetry, decreased pupillary response, and trouble opening or keeping the eye open." "All patients with acute angle-closure glaucoma, hypopyon, hyphema, suspected iritis, keratitis, scleritis, corneal ulcers, or corneal foreign bodies should be urgently evaluated by an ophthalmologist" (StatPearls).
Contact lenses. "Contact lens wearers with bacterial conjunctivitis are at higher risk of bacterial keratitis. They should be asked to remove their contact lenses; treated with topical antibiotics; and promptly evaluated by an ophthalmologist" (CDC).
Herpes viruses. Herpes simplex conjunctivitis may affect one eye with blister-like skin lesions (CDC), and "Patients with herpes simplex conjunctivitis are at the highest risk of complications" (StatPearls). In shingles, "Vesicles on the tip of the nose (Hutchinson sign) are especially indicative of ophthalmic involvement."
Causes & risk factors
Modifiable factors are teaching targets — the patient can act on them.
Signs & symptoms
Each finding tied to the mechanism that produces it — and the triage it calls for.
Diagnostics
Complications
Medications for this condition
Why each class is prescribed here — every card links to its full pharmacology page.
[ALL] Symptom relief. CDC: "Allergy medications and certain eye drops (topical antihistamine and vasoconstrictors), including some prescription eye drops, can also provide relief from allergic conjunctivitis." StatPearls: "Oral antihistamines can also be used for moderate-to-severe allergic conjunctivitis," and "Loratadine is generally preferred for daily use because of a lower sedative effect compared with diphenhydramine." "Prolonged use of vasoconstrictor drops should be avoided because of the risk of rebound conjunctival injection."
[ALL] Longer-term control. StatPearls: seasonal and perennial allergic conjunctivitis "can be treated with topical antihistamines, mast-cell stabilizers, or a combination of both"; mast cell stabilizers "may be prescribed for several weeks, with maximal therapeutic effects achieved after continuous use, making these agents suitable for long-term symptom control." Combination drops such as ketotifen and olopatadine "provide rapid symptom control."
[BAC][CL] Topical antibiotic drops; broad coverage for contact-lens wearers. StatPearls lists ciprofloxacin, ofloxacin, levofloxacin, moxifloxacin and gatifloxacin drops, and notes "No significant differences in outcomes have been observed in trials comparing ophthalmic antibiotic drops of different types." Contact-lens wearers need broad-spectrum coverage, "eg, fluoroquinolones, aminoglycosides, macrolides." Stewardship: "Reserve antibiotics for appropriate bacterial infections to limit unnecessary antimicrobial exposure." Not for viral pink eye. No doses here.
[BAC] Topical azithromycin or erythromycin; part of hyperacute combinations. StatPearls: "Topical erythromycin has been a therapeutic choice for years; however, microbial resistance has limited its usefulness." Hyperacute gonococcal or meningococcal treatment "includes systemic and topical antibiotics (eg, ceftriaxone, azithromycin, fluoroquinolones)." Adult chlamydial (inclusion) conjunctivitis "does not respond to standard antibiotic therapies" and needs systemic treatment with partner treatment.
Beyond medications
- [VIR] Supportive care only. "Antibiotics will NOT improve viral pink eye; these drugs are not effective against viruses" (CDC). Adenoviral conjunctivitis "is self-limiting, and treatment should target symptomatic relief with cold compresses and artificial tears" (StatPearls). It "usually clears up in 7 to 14 days without treatment" but can take 2 to 3 weeks or more (CDC).
- [VIR] Antivirals for herpes. "A doctor can prescribe antiviral medication to treat more serious forms of pink eye (like infection caused by herpes simplex virus or varicella-zoster virus)" (CDC).
- [BAC] Mild bacterial pink eye "usually clears up in 2 to 5 days without treatment but can take 2 weeks to go away completely"; antibiotics "may help shorten the length of infection, reduce complications, and prevent the spread to others" (CDC). "While ointments typically last longer than drops, they tend to interfere with vision" (StatPearls).
- [STI] Gonococcal conjunctivitis (CDC STI Treatment Guidelines 2021): a single dose of intramuscular ceftriaxone; "Providers should consider one-time lavage of the infected eye with saline solution," and consultation with an infectious disease specialist "should be considered." Partners are referred for testing and treatment.
- [ALL] Remove the trigger. "Pink eye caused by an allergen (such as pollen or animal dander) usually improves by removing the allergen from the person's environment" (CDC); artificial tears and cold compresses help (StatPearls).
- Steroid eye drops — eye specialist only. Patients "who may need treatment with steroids should also be referred" to ophthalmology (StatPearls). Steroids "may slow healing, increase the risk of corneal melting, and increase the risk of elevated intraocular pressure"; in allergic disease they are short courses "under specialist supervision with appropriate follow-up."
- Home care. "Use cold compresses and artificial tears to help relieve some of the inflammation and dryness caused by pink eye" (CDC).
Nursing considerations
The RN-specific layer — each action paired with the reason it matters.
How a real nurse thinks
The clinical-judgment loop, worked for a typical presentation — reasoning, not reference.
- 1 Recognize cues
A contact-lens wearer with purulent discharge, eye pain, photophobia and blurred vision that does not clear, and a request to use someone else’s steroid drops.
- 2 Analyze cues
Contact-lens wearers with bacterial conjunctivitis "are at higher risk of bacterial keratitis." Pain, photophobia and vision loss are red flags for a condition other than simple conjunctivitis. Steroids need ophthalmology involvement and can "slow healing, increase the risk of corneal melting."
- 3 Prioritize
Protect vision: remove the lenses and get a prompt ophthalmology evaluation for possible keratitis; stop the steroid plan; prevent spread.
- 4 Generate solutions
Have him remove the lenses; notify the provider for prompt ophthalmology referral and broad-spectrum antibiotic drops; teach that shared or leftover steroid drops are not used; teach hand hygiene, no sharing towels and no lenses until cleared.
- 5 Take action
Assists with lens removal using clean hands and gloves; documents visual acuity and symptoms; arranges same-day ophthalmology; reinforces "Do not share personal items" including eye drops.
- 6 Evaluate
Confirms he was seen by ophthalmology, is using the prescribed drops, has stopped wearing lenses, and knows to return promptly for worse pain or vision.
Scenario — you’re the nurse
Work each question before revealing the answer. Rationales explain the wrong options too.
A 29-year-old man who wears soft contact lenses, including overnight, woke with a red, painful right eye. His partner had pink eye last week.
Q1 Select all that apply Which findings in a patient with a red eye suggest it is NOT simple conjunctivitis? Select all that apply. - A. Moderate to severe eye pain
- B. Light sensitivity
- C. Blurred vision that does not clear when discharge is wiped away
- D. Watery discharge with a cold
- E. Itching of both eyes in spring
Reveal answer & rationale
Q2 Multiple choice A patient with viral conjunctivitis asks for antibiotic eye drops. What is the best response? - A. Antibiotics will clear it within 24 hours
- B. Antibiotics do not help viral pink eye; use cold compresses, artificial tears and careful hand hygiene
- C. Use the antibiotic only in the other eye to prevent spread
- D. Steroid drops work better than antibiotics
Reveal answer & rationale
Q3 Multiple choice A sexually active adult has a massive, rapidly worsening purulent discharge from one eye that began yesterday, with severe lid swelling and decreased vision. What does the nurse anticipate? - A. Warm compresses and follow-up in a week
- B. Emergency evaluation for gonococcal conjunctivitis with systemic and topical antibiotics
- C. An antihistamine eye drop
- D. Reassurance that bacterial pink eye clears in 2 to 5 days
Reveal answer & rationale
Q4 Multiple choice Which instruction about returning to work is consistent with CDC guidance for infectious conjunctivitis? - A. Return as soon as the eye looks less red, without seeing anyone
- B. Return with clinician approval after any indicated treatment; stay home with fever or if close contact cannot be avoided
- C. Stay home for a full 4 weeks
- D. Allergic conjunctivitis requires staying home until it resolves
Reveal answer & rationale
Q5 Multiple choice A patient with seasonal allergic conjunctivitis has been using an over-the-counter redness-relief (vasoconstrictor) drop for 6 weeks and says the redness is worse. What should the nurse explain? - A. Use the drops more often
- B. Prolonged vasoconstrictor use can cause rebound redness; talk with the provider about antihistamine or mast-cell-stabilizer drops
- C. Rub the eyes to relieve the itch
- D. The redness means the allergy is now contagious
Reveal answer & rationale
Common questions
What causes conjunctivitis (pink eye)?
Is pink eye contagious?
How can you tell viral from bacterial pink eye?
When does a red eye need an eye specialist?
Can I use steroid eye drops for pink eye?
How long does pink eye last?
Sources
- Clinical Overview of Pink Eye (Conjunctivitis) (Apr. 15, 2024) — Centers for Disease Control and Prevention
- Treatment of Pink Eye and When to See a Provider — Centers for Disease Control and Prevention
- How to Prevent Pink Eye — Centers for Disease Control and Prevention
- Types of Bacterial Conjunctivitis — Centers for Disease Control and Prevention
- Pink Eye (last updated November 5, 2025) — National Eye Institute (NIH)
- Conjunctivitis Overview — StatPearls — StatPearls (NCBI Bookshelf)
- Bacterial Conjunctivitis — StatPearls — StatPearls (NCBI Bookshelf)
- Viral Conjunctivitis — StatPearls — StatPearls (NCBI Bookshelf)
- Allergic Conjunctivitis — StatPearls — StatPearls (NCBI Bookshelf)
- Sexually Transmitted Infections Treatment Guidelines, 2021 — Gonococcal Infections Among Adolescents and Adults — Centers for Disease Control and Prevention
Reviewed by Hae Suk Lee, RN
Educational summary for nursing students. Scenarios are fictional teaching cases. Always verify against current guidelines and your institution's protocols before acting in practice. Not medical advice.